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杨亦文

编辑:admin  发布日期:2012-04-26

杨亦文

男,1963年生。

1986年7月获浙江大学化学工程专业硕士学位并留校任教。1996年1月至1997年1月在英国爱丁堡大学化学系任访问学者。2004年3月获浙江大学化学工程专业博士学位。现任浙江大学制药工程实验室主任。研究领域包括天然活性物质分离纯化技术、离子液体应用技术和超临界流体技术等。

承担了制药工程专业本科生主干课《制药工艺学》和硕士研究生选修课《工业结晶过程》的教学工作。带学生认识实习2次,生产实习3次。担任化工952班、制药工程02班的班主任。其中制药工程02班被评为校优秀班级。担任制药02和03班的本科生导师。已指导硕士研究生17人。指导本科生毕业论文每届2-3名。

近年来,负责科研项目有天然维生素E产业化技术(浙江省科技计划重点项目,获浙江省科学技术一等奖,黑龙江省科技进步三等奖)、模拟移动床色谱拆分手性药物(教育部博士点专项基金)、天然维生素E琥珀酸酯的新工艺开发(浙江省科技计划重点项目)、表面 活性剂存在下超临界二氧化碳溶解特性研究(浙江省自然基金)等国家级和省部级项目,以及大豆异黄酮生产技术(重大横向,已在黑龙江省产业化)和天然甾醇提取技术(重大横向,已在黑龙江省产业化)等地方重点项目。其中食品功能因子高效分离与制备中的分子修饰与吸附分离耦合技术项目荣获2009年度国家技术发明奖二等奖,全国排名2/6。发表论文50余篇,其中SCI/EI收录30余篇,授权专利5项。

近期取得的与本项目相关的主要成果:

  • Lei, H. J.; Bao, Z. B.; Xing, H. B.; Yang, Y. W.; Ren, Q. L.; Zhao, M. M.; Huang, H. H. Adsorption Behavior of Glucose, Xylose, and Arabinose on Five Different Cation Exchange Resins. J. Chem. Eng. Data. 2010, 55(2), 735-738.
  • Yang, Q. W.; Xing, H. B.; Cao, Y. F.; Su, B. G.; Yang, Y. W.; Ren, Q. L. Selective separation of tocopherol homologues by liquid-liquid extraction using ionic liquids. Ind. Eng. Chem. Res. 2009, 48(13), 6417-6422.
  • Su, B. G.; Bao, Z. B.; Xing, H. B.; Yang, Y. W.; Ren, Q. L. Enantioseparation of paroxetine intermediate on an amylose-derived chiral stationary phase by supercritical fluid chromatography. J. Chromatogr. A. 2009, 1216 (26), 5140-5146.
  • Chen, W.; Su, B. G.; Xing, H. B.; Yang, Y. W.; Ren, Q. L. Solubilities of cholesterol and desmosterol in binary solvent mixtures of n-hexane plus ethanol. Fluid Phase Equilib. 2009,287(1),1-6.
  • Huang, H. H.; Zhao, M. M.; Ren, Q. L.; Yang, Y. W. Changes in inhibitory activity and secondary conformation of soybean trypsin inhibitors induced by tea polyphenol complexation. J. Sci. Food Agric. 2009,89(14),2435-2439.
  • Su, B. G.; Xing, H. B.; Han, Y. S.; Yang, Y. W.; Ren, Q. L.; Wu, P. D. Adsorption Equilibria of cis-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester and cis-4,7,10,13,16,19-Docosahexaenoic Acid Ethyl Ester on C18-Bonded Silica from Supercritical Carbon Dioxide. J. Chem. Eng. Data. 2009, 54(10), 2906-2913.
  • Lu, X. B.; Xing, H. B.; Su, B. G.; Yang, Y. W.; Ren, Q. L. Adsorption behavior of Penicillin G sodium on hydrophilic gel toyopearl HW-40F. J. Chem. Eng. Data. 2009, 54(3),1052-1055.
  • Xing, H. B.; Su, B. G.; Ren, Q. L. Yang. Y. W. Adsorption equilibria of artemisinin from supercritical carbon dioxide on silica gel. J. Supercritic. Fluid. 2009, 49(2),189-195.
  • Chen, W.; Su, B. G.; Xing, H. B.; Yang, Y. W.; Ren, Q. L. Solubility of desmosterol in five organic solvents. J. Chem. Eng. Data. 2008, 53, 2715-2717.
  • Bao, Z. B.; Su, B. G.; Yang, Y. W.; Ren, Q. L. Enantioseparation of paroxetine precursors by HPLC on amylose and tartardiamide-based chiral stationary phases. J. Liq. Chromatogr. R. T. 2008, 31(8), 1147-1161.
  • Yang, Y. W.; Dong, X. Y.; Jin, M. C.; Ren, Q. L. Rapid determination of polycyclic aromatic hydrocarbons in natural tocopherols by highperformance liquid chromatography with fluorescence detection. Food Chem. 2008, 110(1), 226-232.
  • Su, B. G.; Xing, H. B.; Yang, Y. W.; Ren, Q.L. Solubility of Oxymatrine in Supercritical Carbon Dioxide. J. Chem. Eng. Data 2008, 53(7), 1672-1674.
  • Jin, M. C.; OuYang, X.; Yang, Y. W.; Ren, Q. L. Quantification of tripdiolide in human whole blood by liquid chromatography coupled with atmospheric pressure chemical ionization tandem mass spectrometry. Talanta 2007, 72(2), 582-586.
  • Jin, M. C.; Yang, Y. W.; Su, B. G.; Ren, Q. L. Determination of soyasaponins Ba and Bb in human serum by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. J. Chromatogr. B 2007, 846(1-2), 169-175.
  • Yang, Y. W.; Jin, M. C.; Huang, M.; Su, B. G.; Ren, Q. L. Ultrasound-assisted extraction of soyasaponins from hypocotyls, and analysis by LC-ESI-MS. Chromatographia 2007, 65(9-10), 555-560.
  • Han, Y. S.; Yang, Y. W.; Wu, P. D. Binary diffusion coefficients of arachidonic acid ethyl esthers, cis-5,8,11,14,17-eicosapentaenoic acid ethyl esthers, and cis-4,7,10,13,16,19- docosahexanenoic acid ethyl esthers in supercritical carbon dioxide. J. Chem. Eng. Data 2007, 52(2), 555-559.
  • Su, B. G.; Lv, X. B.; Yang, Y. W.; Ren, Q. L. Solubilities of dodecylpolyoxyethylene polyoxypropylene ether in supercritical carbon dioxide. J. Chem. Eng. Data 2006, 51(2), 542-544.
  • Jin, M. C.; Yang, Y. W.; Su, B. G.; Ren, Q. L. Rapid quantification and characterization of soyasaponins by high-performance liquid chromatography coupled with electrospray mass spectrometry. J. Chromatogr. A 2006,1108, 31-37.
  • Jin, M. C.; Yang, Y. W. Simultaneous determination of trace mono- and di-chlorophenols in water by ion chromatography atmospheric pressure chemical ionization mass spectrometry. Ana. Chim. Acta. 2006, 566 (2), 193-199.
  • Liu, B. J.; Yang, Y. W.; Ren Q. L. Parallel Pore and Surface Diffusion of Levulinic Acid in Basic Polymeric Adsorbents. J. Chromatogr. A 2006,1132 (1-2), 190-200.
  • Jin, M. C.; Yang, Y. W.; Su, B. G.; Ren, Q. L. Determination of soyasaponins Ba and Bb in human serum by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. J. Chromatogr. B 2007,846, 169-175.
  • Lv, Y. B.; Yang, Y. W.; Wu, P. D. Separation of phosphatidylcholine from soybean phospholipids by simulated moving bed. J. Zhejiang Univ. Sci. B 2006, 7(7), 559-564.
  • Zhang, Y. Y.; Yang, Y. W.; Jiang, Hailiang; Ren, Q. L. Quantification of soybean phospholipids in soybean Degummed oil residue by HPLC with evaporative light scattering detectrion. J. Liq. Chromatogr. R. T. 2005, 28(9), 1333-1343.
  • Qian, G. P.; Yang, Y. W.; Ren, Q. L. Determination of artemisinin in Artemisia annua L. by reversed phase HPLC. J. Liq. Chromatogr. R. T. 2005, 28(5), 705-712.
  • Yang, Y. W.; Su, B. G.; Yan, Q. H.; Ren, Q. L. Separation of naproxen enantiomers by supercritical/subcritical fluid chromatography. J. Pharm. Biomed. 2005, 39(4), 815-818.
  • Xing, H. B.; Yang, Y. W.; Su, B. G.; Huang, M.; Ren, Q. L. Solubility of Artemisinin in Supercritical Carbon Dioxide. J. Chem. Eng. Data 2003, 48, 330-332.

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